Linear and nonlinear Raman microspectroscopy: History, instrumentation, and applications

Hideaki Kano, Hiroki Segawa, Philippe Leproux, Vincent Couderc

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)


Through carrying out Raman spectroscopy under a microscope, we can observe the molecular distribution and dynamics of living cells in situ without staining or labeling. In general, Raman microscopy/microspectroscopy is classified into spontaneous Raman microscopy/microspectroscopy and nonlinear Raman microscopy/microspectroscopy. This review will first summarize the historical development of Raman microscopes, and will discuss in detail their instrumentation and applications.

Original languageEnglish
Pages (from-to)752-761
Number of pages10
JournalOptical Review
Issue number6
Publication statusPublished - Nov 27 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics


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