Linear and nonlinear laser-trapping microrheology

C. F. Schmidt, D. Mizuno

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)


We have developed a high-bandwidth technique for active 2-particle microrheology (AMR) with which we can probe linear and nonlinear responses of soft materials. Micron-sized colloidal probe particles are driven by an oscillating optical trap, and the resulting correlated motions of neighboring particles are detected by laser interferometry. Lock-in detection at the driving frequency and at its second harmonic makes it possible to measure the linear and the non-linear response of the embedding medium at the same time. We demonstrate the sensitivity of the method by detecting a second-harmonic response in water which is of purely geometric origin and which can be fully understood within linear hydrodynamics.

Original languageEnglish
Title of host publicationOptical Trapping and Optical Micromanipulation IV
Publication statusPublished - 2007
EventOptical Trapping and Optical Micromanipulation IV - San Diego, CA, United States
Duration: Aug 26 2007Aug 29 2007

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


OtherOptical Trapping and Optical Micromanipulation IV
Country/TerritoryUnited States
CitySan Diego, CA

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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