Abstract
Lifestyle-related diseases such as type 2 diabetes, hypertension and dyslipidemia are a prominent cause of mortality in Japan, and there is a strong requirement for elucidation of detailed molecular mechanisms and effective therapeutic strategies. Obesity-induced adipose tissue inflammation leads to dysregulation of adipokine production, which can cause lifestyle-related diseases. The interaction of organ systems via endocrine or neural networks is recognized as an important factor in the pathogenesis and promotion of lifestyle-related diseases. Therefore, further investigation for the interaction between adipose tissues and bones can provide new treatment strategies of metabolic bone disorders.
Original language | English |
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Pages (from-to) | 392-398 |
Number of pages | 7 |
Journal | Clinical calcium |
Volume | 26 |
Issue number | 3 |
Publication status | Published - Mar 1 2016 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Medicine(all)