Lesions of the ventromedial hypothalamic nucleus enhance sympatho-adrenal function

Hironobu Yoshimatsu, Yutaka Oomura, Toshihiko Katafuchi, Akira Niijima, Akio Sato

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


The effects of lesions of the ventromedial hypothalamic nucleus (VMH) on the sympatho-adrenal function were investigated in anesthetized rats using electrophysiological and biochemical techniques. Lesions of this nucleus produced a gradual but strong increase in the efferent activity of the adrenal sympathetic nerves. Catecholamine secretion from the adrenal medulla was also facilitated by VMH lesions. The results indicate that the catecholamines from the adrenal medulla might be involved in the development of metabolic disorders seen during VMH syndrome.

Original languageEnglish
Pages (from-to)390-392
Number of pages3
JournalBrain Research
Issue number2
Publication statusPublished - Jul 29 1985

All Science Journal Classification (ASJC) codes

  • General Neuroscience
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology


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