Leiomyosarcoma in the humerus with leukocytosis and elevation of serum G-CSF

Takeaki Ishii, Akio Sakamoto, Shuichi Matsuda, Yoshihiro Matsumoto, Katsumi Harimaya, Yusuke Takahashi, Yoshinao Oda, Yukihide Iwamoto

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1 Citation (Scopus)


Leukocytosis associated with secretion of granulocyte colony-stimulating factor (G-CSF) has been reported in various tumors, primarily poorly differentiated epithelial tumors, but is extremely rare in bone tumors. An 84-yearold woman experienced swelling and pain in the shoulder for 1 month. Leukocytosis and elevated serum G-CSF were observed, but resolved following tumor resection. A diagnosis of leiomyosarcoma of the bone with expression of GCSF was confirmed immunohistochemically. Histological diagnosis of leiomyosarcoma showed it to be differentiated, which is unusual for G-CSF-secreting tumors.

Original languageEnglish
Pages (from-to)719-723
Number of pages5
JournalSkeletal Radiology
Issue number6
Publication statusPublished - Jun 2012

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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