Knee kinematics in medial osteoarthritis during in vivo weight-bearing activities

Satoshi Hamai, Taka Aki Moro-oka, Hiromasa Miura, Takeshi Shimoto, Hidehiko Higaki, Benjamin J. Fregly, Yukihide Iwamoto, Scott A. Banks

Research output: Contribution to journalArticlepeer-review

78 Citations (Scopus)


Dynamic knee kinematics were analyzed for medial osteoarthritic (OA) knees in three activities, including two types of maximum knee flexion. Continuous x-ray images of kneeling, squatting, and stair climbing motions were taken using a large flat panel detector. CT-derived bone models were used for the model registration-based 3D kinematic measurements. Three-dimensional joint kinematics and contact locations were determined using two methods: bone-fixed coordinate systems and by interrogation of CT-based bone model surfaces. The femur exhibited gradual external rotation with knee flexion for kneeling and squatting activities, and gradual internal rotation with knee extension for stair climbing. From 1008 to 1208 flexion, contact locations showed amedial pivot pattern similar to normal knees. However, knees with medial OA displayed a femoral internal rotation bias and less posterior translation when compared with normal knees. A classic screw-home movement was not observed in OA knees near extension. Decreased variability with both activities and methods of calculation were demonstrated for all three activities. In conclusion, the weight-bearing kinematics of patients with medial OA differs from normal knees. Pathological changes of the articulating surfaces and the ligaments correspond to observed abnormalities in knee kinematics.

Original languageEnglish
Pages (from-to)1555-1561
Number of pages7
JournalJournal of Orthopaedic Research
Issue number12
Publication statusPublished - Dec 2009

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine


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