Abstract
A hematoside-type ganglioside, LLG-1 (1), has been obtained from the polar lipid fraction of the chloro- form/methanol extract of the starfish Linckia laevigata. The structure of the ganglioside has been determined on the basis of chemical and spectroscopic evidence as 1-0-[N-glycolyl-α-D-neuraminosyl- (2→3)-β-D-galactopyra-nosyl-(1→4)-β-D-glucopyranosyl] -ceramide. The ceramide moiety was composed of heterogeneous 2-hydroxy fatty acid and phytosphingosine units. This is the first report on the isolation and structure elucidation of naked hematoside-type ganglioside from echinoderms.
| Original language | English |
|---|---|
| Pages (from-to) | 204-206 |
| Number of pages | 3 |
| Journal | Chemical and Pharmaceutical Bulletin |
| Volume | 57 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2009 |
All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Drug Discovery