TY - JOUR
T1 - Is there a role of adjuvant treatment for salivary duct carcinoma
AU - Nakashima, T.
AU - Yasumatsu, R.
AU - Toh, S.
AU - Hashimoto, K.
AU - Shinoto, M.
AU - Nakamura, K.
AU - Komune, S.
N1 - Publisher Copyright:
© 2015 JLO (1984) Limited.
PY - 2015
Y1 - 2015
N2 - objective: To determine the clinical effect of post-operative radiotheraphy and systemic chemotherapy for the treatment of salivary duct carcinoma. Study design: Retrospective review. Design: The medical records of 26 patients treated by surgery with or without radiotheraphy and/or systemic chemotherapy for salivary duct carcinoma were retrospectively reviewed to investigate the role of post-operative adjuvant treatment for the patients' prognosis. Results: The overall three-year and five-year survival rates were 54 and 48.1 per cent, respectively. There was no correlation with the clinical stage and the patients' prognosis. The overall three-year survival of the patients with or without post-operative radiotheraphy was 64 and 33 per cent, respectively (p = 0.29). The overall three-year survival of the patients with or without post-operative chemotherapy was 53 and 56 per cent, respectively (p = 0.78). Conclusion: Post-operative adjuvant therapy did not improve the patients' overall prognosis with salivary duct carcinoma. Developing novel treatment modalities may be necessary to improve the prognosis of this aggressive disease.
AB - objective: To determine the clinical effect of post-operative radiotheraphy and systemic chemotherapy for the treatment of salivary duct carcinoma. Study design: Retrospective review. Design: The medical records of 26 patients treated by surgery with or without radiotheraphy and/or systemic chemotherapy for salivary duct carcinoma were retrospectively reviewed to investigate the role of post-operative adjuvant treatment for the patients' prognosis. Results: The overall three-year and five-year survival rates were 54 and 48.1 per cent, respectively. There was no correlation with the clinical stage and the patients' prognosis. The overall three-year survival of the patients with or without post-operative radiotheraphy was 64 and 33 per cent, respectively (p = 0.29). The overall three-year survival of the patients with or without post-operative chemotherapy was 53 and 56 per cent, respectively (p = 0.78). Conclusion: Post-operative adjuvant therapy did not improve the patients' overall prognosis with salivary duct carcinoma. Developing novel treatment modalities may be necessary to improve the prognosis of this aggressive disease.
UR - http://www.scopus.com/inward/record.url?scp=84953343035&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84953343035&partnerID=8YFLogxK
U2 - 10.1017/S0022215114002965
DO - 10.1017/S0022215114002965
M3 - Article
C2 - 25706173
AN - SCOPUS:84953343035
SN - 0022-2151
VL - 129
SP - S98-S101
JO - Journal of Laryngology and Otology
JF - Journal of Laryngology and Otology
IS - S2
ER -