Involvement of the novel two-component nsrrs and lcrrs systems in distinct resistance pathways against nisin a and nukacin isk-1 in streptococcus mutans

miki Kawada-Matsuo, Yuichi Oogai, Takeshi Zendo, Junichi Nagao, Yukie Shibata, Yoshihisa Yamashita, Yoshitoshi Ogura, Tetsuya Hayashi, Kenji Sonomoto, Hitoshi Komatsuzawa

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

The novel two-component systems nsrrs and lcrrs are individually associated with resistance against the distinct lantibiotics nisin a and nukacin isk-1 in streptococcus mutans. nsrrs regulates the expression of nsrx, which is associated with nisin a binding, and lcrrs regulates the expression of the abc transporter lctfeg.

Original languageEnglish
Pages (from-to)4751-4755
Number of pages5
JournalApplied and environmental microbiology
Volume79
Issue number15
DOIs
Publication statusPublished - Aug 2013

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

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