Investigation of DNA strand exchange mechanisms mediated by cationic polymers.

Yuichi Sato; Won Jong Kim; Sung Won Choi; Minako Saito; Arihiro Kano; Toshihiro Akaike; Atsushi Maruyama

doi:10.1093/nass/2.1.59

Investigation of DNA strand exchange mechanisms mediated by cationic polymers.

Yuichi Sato, Won Jong Kim, Sung Won Choi, Minako Saito, Arihiro Kano, Toshihiro Akaike, Atsushi Maruyama

Research output: Contribution to journal › Article › peer-review

Abstract

It was observed that conjugation of dextran for PLL provided PLL-g-Dex with new properties of enhancing and accelerating inter-nucleotide recognition (1, 2, 3). In this paper, we report the effects of cationic PLL-g-Dex copolymers on base-pair formation of self-complementary octamer oligonucleotide by using NMR and CD analysis. NMR studies revealed that PLL-g-Dex copolymer did not affect hydrogen-bondings between bases in DNA duplex. CD studies also supported inert nature of the copolymer upon hybrid structure.

Original language	English
Pages (from-to)	59-60
Number of pages	2
Journal	Nucleic acids research. Supplement (2001)
Issue number	2
DOIs	https://doi.org/10.1093/nass/2.1.59
Publication status	Published - 2002
Externally published	Yes

All Science Journal Classification (ASJC) codes

Medicine(all)

Access to Document

10.1093/nass/2.1.59

Cite this

@article{bcd9d2b38a0541eab132ec1daa77d695,

title = "Investigation of DNA strand exchange mechanisms mediated by cationic polymers.",

abstract = "It was observed that conjugation of dextran for PLL provided PLL-g-Dex with new properties of enhancing and accelerating inter-nucleotide recognition (1, 2, 3). In this paper, we report the effects of cationic PLL-g-Dex copolymers on base-pair formation of self-complementary octamer oligonucleotide by using NMR and CD analysis. NMR studies revealed that PLL-g-Dex copolymer did not affect hydrogen-bondings between bases in DNA duplex. CD studies also supported inert nature of the copolymer upon hybrid structure.",

author = "Yuichi Sato and Kim, {Won Jong} and Choi, {Sung Won} and Minako Saito and Arihiro Kano and Toshihiro Akaike and Atsushi Maruyama",

year = "2002",

doi = "10.1093/nass/2.1.59",

language = "English",

pages = "59--60",

journal = "Nucleic acids research. Supplement (2001)",

publisher = "Oxford University Press",

number = "2",

}

TY - JOUR

T1 - Investigation of DNA strand exchange mechanisms mediated by cationic polymers.

AU - Sato, Yuichi

AU - Kim, Won Jong

AU - Choi, Sung Won

AU - Saito, Minako

AU - Kano, Arihiro

AU - Akaike, Toshihiro

AU - Maruyama, Atsushi

PY - 2002

Y1 - 2002

N2 - It was observed that conjugation of dextran for PLL provided PLL-g-Dex with new properties of enhancing and accelerating inter-nucleotide recognition (1, 2, 3). In this paper, we report the effects of cationic PLL-g-Dex copolymers on base-pair formation of self-complementary octamer oligonucleotide by using NMR and CD analysis. NMR studies revealed that PLL-g-Dex copolymer did not affect hydrogen-bondings between bases in DNA duplex. CD studies also supported inert nature of the copolymer upon hybrid structure.

AB - It was observed that conjugation of dextran for PLL provided PLL-g-Dex with new properties of enhancing and accelerating inter-nucleotide recognition (1, 2, 3). In this paper, we report the effects of cationic PLL-g-Dex copolymers on base-pair formation of self-complementary octamer oligonucleotide by using NMR and CD analysis. NMR studies revealed that PLL-g-Dex copolymer did not affect hydrogen-bondings between bases in DNA duplex. CD studies also supported inert nature of the copolymer upon hybrid structure.

UR - http://www.scopus.com/inward/record.url?scp=0041818211&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0041818211&partnerID=8YFLogxK

U2 - 10.1093/nass/2.1.59

DO - 10.1093/nass/2.1.59

M3 - Article

C2 - 12903104

AN - SCOPUS:0041818211

SP - 59

EP - 60

JO - Nucleic acids research. Supplement (2001)

JF - Nucleic acids research. Supplement (2001)

IS - 2

ER -

Investigation of DNA strand exchange mechanisms mediated by cationic polymers.

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this