TY - JOUR
T1 - Intravascular Large B-Cell Lymphoma Complicated by Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis that was Successfully Treated with Rituximab-Containing Chemotherapy
AU - Tsuda, Mariko
AU - Nakashima, Yasuhiro
AU - Ikeda, Motohiko
AU - Shimada, Shingo
AU - Nomura, Masatoshi
AU - Matsushima, Takamitsu
AU - Takahashi, Shunsuke
AU - Aishima, Shinichi
AU - Oda, Yoshinao
AU - Shiratsuchi, Motoaki
AU - Takayanagi, Ryoichi
PY - 2015
Y1 - 2015
N2 - A 64-year-old woman had suffered from painful livedo reticularis for 2 years and was referred to us due to fever, anasarca and paresthesia of the lower limbs. Serum proteinase-3-anti-neutrophil cytoplasmic antibody (ANCA) was positive. Abnormal lymphocytes were found in the cerebrospinal fluid and bone marrow. Skin biopsy revealed large atypical lymphoid cells with CD20 positivity lodged in the small vessels and neutrophilic infiltration into the arterial vascular wall with fibrinoid degeneration. A diagnosis of intravascular large B-cell lymphoma complicated by ANCA-associated vasculitis was made, and rituximab-containing chemotherapy followed by prednisolone was quite effective for both lymphoma and ANCA-associated vasculitis.
AB - A 64-year-old woman had suffered from painful livedo reticularis for 2 years and was referred to us due to fever, anasarca and paresthesia of the lower limbs. Serum proteinase-3-anti-neutrophil cytoplasmic antibody (ANCA) was positive. Abnormal lymphocytes were found in the cerebrospinal fluid and bone marrow. Skin biopsy revealed large atypical lymphoid cells with CD20 positivity lodged in the small vessels and neutrophilic infiltration into the arterial vascular wall with fibrinoid degeneration. A diagnosis of intravascular large B-cell lymphoma complicated by ANCA-associated vasculitis was made, and rituximab-containing chemotherapy followed by prednisolone was quite effective for both lymphoma and ANCA-associated vasculitis.
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U2 - 10.3960/jslrt.55.39
DO - 10.3960/jslrt.55.39
M3 - Article
C2 - 26106006
AN - SCOPUS:84991971522
SN - 1346-4280
VL - 55
SP - 39
EP - 43
JO - Journal of clinical and experimental hematopathology : JCEH
JF - Journal of clinical and experimental hematopathology : JCEH
IS - 1
ER -