Intraosseous synovial sarcoma of the mandible: A case report and review of the literature

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Synovial sarcoma (SS) is a malignant soft tissue tumor that usually arises in the para‑articular regions of the extremities. Only nine cases of SS in the mandible have been reported to date. The present study described a case of SS arising from the left mandible. A 54‑year‑old woman was referred to Kyushu University Hospital (Fukuoka, Japan) with a complaint of numbness in the left mental nerve area. Computed tomography revealed replacement of the left mandibular bone marrow with soft tissue and destruction of the mandibular canal. Magnetic resonance imaging revealed an isointense mass on T1‑weighted images and hyperintensity on T2‑weighted images. The tumor showed homogeneous enhancement. A biopsy was performed, and monophasic SS was diagnosed based on immunohistochemical staining features and genetic analysis. Hemimandible dissection and supraomophyoid neck resection were performed with fibular osteocutaneous flap reconstruction, followed by adjuvant chemotherapy. There was no evidence of recurrence or distant metastases. The present study also reviewed the clinical, imaging, histological, and immunohistochemical features of the SS in the mandible.

Original languageEnglish
Article number318
JournalOncology Letters
Volume26
Issue number1
DOIs
Publication statusPublished - Jul 2023

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Fingerprint

Dive into the research topics of 'Intraosseous synovial sarcoma of the mandible: A case report and review of the literature'. Together they form a unique fingerprint.

Cite this