Intrahepatic cholangiocarcinoma: Its mode of spreading and therapeutic modalities

Ken Shirabe, Mitsuo Shimada, Norifumi Harimoto, Keishi Sugimachi, Yo Ichi Yamashita, Eiji Tsujita, Shin Ichi Aishima

Research output: Contribution to journalArticlepeer-review

85 Citations (Scopus)


Intrahepatic cholangiocarcinoma (IHCC) is a primary adenocarcinoma of the liver, arising from the intrahepatic bile ducts. The prognosis is generally poor because locoregional extension is usually advanced at the time of diagnosis. Even after a resection, the outcome for patients with advanced IHCC is extremely poor, and the presence of lymph node metastasis has been reported in most previous studies to be the worst prognostic factor after a resection. There are no clear guidelines on lymph node dissection with IHCC. In this article, we review the mode of invasion and the therapeutic modalities: hepatic resection, lymph node dissection, liver transplantation, radiation, and chemotherapy for IHCC.

Original languageEnglish
Pages (from-to)S159-S164
Issue number1 SUPPL.
Publication statusPublished - 2002

All Science Journal Classification (ASJC) codes

  • Surgery


Dive into the research topics of 'Intrahepatic cholangiocarcinoma: Its mode of spreading and therapeutic modalities'. Together they form a unique fingerprint.

Cite this