International consensus statement on major depressive disorder.

David J. Nutt, Jonathan R.T. Davidson, Alan J. Gelenberg, Teruhiko Higuchi, Shigenobu Kanba, Oǧuz Karamustafalioǧlu, George I. Papakostas, Kaoru Sakamoto, Takeshi Terao, Mingyuan Zhang

Research output: Contribution to journalArticlepeer-review

61 Citations (Scopus)


Because considerable variability exists between countries in the management of major depressive disorder, experts in psychiatry gathered for the International Consensus Group on Depression to outline a universal treatment algorithm for this illness. The experts decided to adapt the existing treatment algorithm developed in Japan and discuss strategies for clinical issues that have been problematic in some countries. Specific recommendations were made by the consensus group for screening for, diagnosing, and treating depression, which include periodically screening all patients for depression, completing a differential diagnosis of depression, referring to a psychiatric specialist if needed, establishing a therapeutic alliance with patients and their families, choosing and optimizing the dose of appropriate antidepressants based on individual patient's needs, and incorporating nonpharmacologic treatment strategies as necessary.

Original languageEnglish
Pages (from-to)e08
JournalThe Journal of clinical psychiatry
Volume71 Suppl E1
Publication statusPublished - 2010

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health


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