Integrating LSPR and SERS for Rapid and Effective Visualization and Identification of Volatile Organic Compounds Distribution

Microbial volatile organic compounds (MVOCs) can serve as a diagnostic tool for assessing the respiratory status of microorganisms. Localized surface plasmon resonance (LSPR) sensors are noted for their rapid response and straightforward operation; however, they often struggle to provide specific information about the detected substances and to differentiate between gas types. In contrast, gas sensors utilizing surface-enhanced Raman spectroscopy (SERS) technology offer excellent selectivity and can generate unique 'fingerprint' signals, enabling easy identification and distinction of various gas molecules. Integrating these two technologies promises to enhance the visualization of volatile organic compound distributions both more effectively and expeditiously.