Integrated view of the human chromosome x-centric proteome project

Tadashi Yamamoto; Keiichi Nakayama; Hisashi Hirano; Takeshi Tomonaga; Yasushi Ishihama; Tetsushi Yamada; Tadashi Kondo; Yoshio Kodera; Yuichi Sato; Norie Araki; Hiroshi Mamitsuka; Naoki Goshima

doi:10.1021/pr300844p

Integrated view of the human chromosome x-centric proteome project

Tadashi Yamamoto, Keiichi Nakayama, Hisashi Hirano, Takeshi Tomonaga, Yasushi Ishihama, Tetsushi Yamada, Tadashi Kondo, Yoshio Kodera, Yuichi Sato, Norie Araki, Hiroshi Mamitsuka, Naoki Goshima

Department of Molecular and Cellular Biology

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

This article introduces how the human chromosome Xcentric proteome project is carried out by the Japan Chromosome X Project Consortium. The inactivation of one of two chromosomes in female mammals and accumulation of genes related to neural/immune systems/tumor/testis are characteristic of chromosome X. In this Chromosome X Project, information on proteins translated from genes on chromosome X is collected by both mass spectrometry-and antibody-based proteomics. Information on the following resources is also provided: antibodies to proteins translated and full-length cDNAs transcripted from the chromosome X genes for recombinant proteins. The consortium aims to provide the following tools to search useful antibodies in the literature (Antibody Ranker), to find gene expression sites in microarray databases (Transcript Localizer) and to do advanced MRM analysis (information-based MRM).

Original language	English
Pages (from-to)	58-61
Number of pages	4
Journal	Journal of Proteome Research
Volume	12
Issue number	1
DOIs	https://doi.org/10.1021/pr300844p
Publication status	Published - Jan 4 2013

All Science Journal Classification (ASJC) codes

Chemistry(all)
Biochemistry

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10.1021/pr300844p

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title = "Integrated view of the human chromosome x-centric proteome project",

abstract = "This article introduces how the human chromosome Xcentric proteome project is carried out by the Japan Chromosome X Project Consortium. The inactivation of one of two chromosomes in female mammals and accumulation of genes related to neural/immune systems/tumor/testis are characteristic of chromosome X. In this Chromosome X Project, information on proteins translated from genes on chromosome X is collected by both mass spectrometry-and antibody-based proteomics. Information on the following resources is also provided: antibodies to proteins translated and full-length cDNAs transcripted from the chromosome X genes for recombinant proteins. The consortium aims to provide the following tools to search useful antibodies in the literature (Antibody Ranker), to find gene expression sites in microarray databases (Transcript Localizer) and to do advanced MRM analysis (information-based MRM).",

author = "Tadashi Yamamoto and Keiichi Nakayama and Hisashi Hirano and Takeshi Tomonaga and Yasushi Ishihama and Tetsushi Yamada and Tadashi Kondo and Yoshio Kodera and Yuichi Sato and Norie Araki and Hiroshi Mamitsuka and Naoki Goshima",

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AU - Yamamoto, Tadashi

AU - Nakayama, Keiichi

AU - Hirano, Hisashi

AU - Tomonaga, Takeshi

AU - Ishihama, Yasushi

AU - Yamada, Tetsushi

AU - Kondo, Tadashi

AU - Kodera, Yoshio

AU - Sato, Yuichi

AU - Araki, Norie

AU - Mamitsuka, Hiroshi

AU - Goshima, Naoki

PY - 2013/1/4

Y1 - 2013/1/4

N2 - This article introduces how the human chromosome Xcentric proteome project is carried out by the Japan Chromosome X Project Consortium. The inactivation of one of two chromosomes in female mammals and accumulation of genes related to neural/immune systems/tumor/testis are characteristic of chromosome X. In this Chromosome X Project, information on proteins translated from genes on chromosome X is collected by both mass spectrometry-and antibody-based proteomics. Information on the following resources is also provided: antibodies to proteins translated and full-length cDNAs transcripted from the chromosome X genes for recombinant proteins. The consortium aims to provide the following tools to search useful antibodies in the literature (Antibody Ranker), to find gene expression sites in microarray databases (Transcript Localizer) and to do advanced MRM analysis (information-based MRM).

AB - This article introduces how the human chromosome Xcentric proteome project is carried out by the Japan Chromosome X Project Consortium. The inactivation of one of two chromosomes in female mammals and accumulation of genes related to neural/immune systems/tumor/testis are characteristic of chromosome X. In this Chromosome X Project, information on proteins translated from genes on chromosome X is collected by both mass spectrometry-and antibody-based proteomics. Information on the following resources is also provided: antibodies to proteins translated and full-length cDNAs transcripted from the chromosome X genes for recombinant proteins. The consortium aims to provide the following tools to search useful antibodies in the literature (Antibody Ranker), to find gene expression sites in microarray databases (Transcript Localizer) and to do advanced MRM analysis (information-based MRM).

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Integrated view of the human chromosome x-centric proteome project

Abstract

All Science Journal Classification (ASJC) codes

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