Integrated view of the human chromosome x-centric proteome project

Tadashi Yamamoto, Keiichi Nakayama, Hisashi Hirano, Takeshi Tomonaga, Yasushi Ishihama, Tetsushi Yamada, Tadashi Kondo, Yoshio Kodera, Yuichi Sato, Norie Araki, Hiroshi Mamitsuka, Naoki Goshima

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)


This article introduces how the human chromosome Xcentric proteome project is carried out by the Japan Chromosome X Project Consortium. The inactivation of one of two chromosomes in female mammals and accumulation of genes related to neural/immune systems/tumor/testis are characteristic of chromosome X. In this Chromosome X Project, information on proteins translated from genes on chromosome X is collected by both mass spectrometry-and antibody-based proteomics. Information on the following resources is also provided: antibodies to proteins translated and full-length cDNAs transcripted from the chromosome X genes for recombinant proteins. The consortium aims to provide the following tools to search useful antibodies in the literature (Antibody Ranker), to find gene expression sites in microarray databases (Transcript Localizer) and to do advanced MRM analysis (information-based MRM).

Original languageEnglish
Pages (from-to)58-61
Number of pages4
JournalJournal of Proteome Research
Issue number1
Publication statusPublished - Jan 4 2013

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • Biochemistry


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