Initial adhesion of fibroblasts on thin rubber scaffolds

Shinichiro Shimomura; Hisao Matsuno; Toshiyuki Ohta; Seiichi Kawahara; Keiji Tanaka

doi:10.1246/cl.160061

Initial adhesion of fibroblasts on thin rubber scaffolds

Shinichiro Shimomura, Hisao Matsuno, Toshiyuki Ohta, Seiichi Kawahara, Keiji Tanaka

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Cell adhesion behaviors on thin synthetic and natural rubbers supported on solid substrates were examined. When the film was thinner than 60 nm, the adhesion of L929 fibroblasts was clearly promoted. This can be explained in terms of the manifestation of mechanical response from the hard solid substrate. Protein-free natural rubber exhibited better performance than polyisoprene as a scaffold.

Original language	English
Pages (from-to)	475-477
Number of pages	3
Journal	Chemistry Letters
Volume	45
Issue number	4
DOIs	https://doi.org/10.1246/cl.160061
Publication status	Published - 2016

All Science Journal Classification (ASJC) codes

Chemistry(all)

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10.1246/cl.160061

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title = "Initial adhesion of fibroblasts on thin rubber scaffolds",

abstract = "Cell adhesion behaviors on thin synthetic and natural rubbers supported on solid substrates were examined. When the film was thinner than 60 nm, the adhesion of L929 fibroblasts was clearly promoted. This can be explained in terms of the manifestation of mechanical response from the hard solid substrate. Protein-free natural rubber exhibited better performance than polyisoprene as a scaffold.",

author = "Shinichiro Shimomura and Hisao Matsuno and Toshiyuki Ohta and Seiichi Kawahara and Keiji Tanaka",

note = "Funding Information: This research was partly supported by JSPS KAKENHI Scientific Research on Innovative Area {"}New Polymeric Materials Based on Element-Blocks{"} (No. 15H00758) program, Grant-in-Aids for Scientific Research (A) (No. 15H02183) and (C) (No. 15K05633). Publisher Copyright: {\textcopyright} 2016 The Chemical Society of Japan.",

year = "2016",

doi = "10.1246/cl.160061",

language = "English",

volume = "45",

pages = "475--477",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "The Chemical Society of Japan",

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TY - JOUR

T1 - Initial adhesion of fibroblasts on thin rubber scaffolds

AU - Shimomura, Shinichiro

AU - Matsuno, Hisao

AU - Ohta, Toshiyuki

AU - Kawahara, Seiichi

AU - Tanaka, Keiji

N1 - Funding Information: This research was partly supported by JSPS KAKENHI Scientific Research on Innovative Area "New Polymeric Materials Based on Element-Blocks" (No. 15H00758) program, Grant-in-Aids for Scientific Research (A) (No. 15H02183) and (C) (No. 15K05633). Publisher Copyright: © 2016 The Chemical Society of Japan.

PY - 2016

Y1 - 2016

N2 - Cell adhesion behaviors on thin synthetic and natural rubbers supported on solid substrates were examined. When the film was thinner than 60 nm, the adhesion of L929 fibroblasts was clearly promoted. This can be explained in terms of the manifestation of mechanical response from the hard solid substrate. Protein-free natural rubber exhibited better performance than polyisoprene as a scaffold.

AB - Cell adhesion behaviors on thin synthetic and natural rubbers supported on solid substrates were examined. When the film was thinner than 60 nm, the adhesion of L929 fibroblasts was clearly promoted. This can be explained in terms of the manifestation of mechanical response from the hard solid substrate. Protein-free natural rubber exhibited better performance than polyisoprene as a scaffold.

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U2 - 10.1246/cl.160061

DO - 10.1246/cl.160061

M3 - Article

AN - SCOPUS:84964596754

SN - 0366-7022

VL - 45

SP - 475

EP - 477

JO - Chemistry Letters

JF - Chemistry Letters

IS - 4

ER -

Initial adhesion of fibroblasts on thin rubber scaffolds

Abstract

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