Influence of synovia constituents on tribological behaviors of articular cartilage

Teruo Murakami, Seido Yarimitsu, Kazuhiro Nakashima, Yoshinori Sawae, Nobuo Sakai

Research output: Contribution to journalArticlepeer-review

53 Citations (Scopus)


The extremely low friction and minimal wear in natural synovial joints appear to be established by effective lubrication mechanisms based on appropriate combination of articular cartilage and synovial fluid. The complex structure of cartilage composed of collagen and proteoglycan with high water content contributes to high load-carrying capacity as biphasic materials and the various constituents of synovial fluid play important roles in various lubrication mechanisms. However, the detailed differences in functions of the intact and damaged cartilage tissues, and the interaction or synergistic action of synovia constituents with articular cartilage have not yet been clarified. In this study, to examine the roles of synovia constituents and the importance of cartilage surface conditions, the changes in friction were observed in the reciprocating tests of intact and damaged articular cartilage specimens against glass plate lubricated with lubricants containing phospholipid, protein and/or hyaluronic acid as main constituents in synovial fluid. The effectiveness of lubricant constituents and the influence of cartilage surface conditions on friction are discussed. In addition, the protectiveness by synovia constituents for intact articular cartilage surfaces is evaluated.

Original languageEnglish
Pages (from-to)150-162
Number of pages13
Issue number2
Publication statusPublished - Jun 1 2013

All Science Journal Classification (ASJC) codes

  • Mechanical Engineering
  • Surfaces, Coatings and Films


Dive into the research topics of 'Influence of synovia constituents on tribological behaviors of articular cartilage'. Together they form a unique fingerprint.

Cite this