TY - GEN
T1 - Inducing blood vessel formation using cubic eggshell with patterned surface
AU - Huang, Wenjing
AU - Arai, Fumihito
AU - Kawahara, Tomohiro
N1 - Publisher Copyright:
© 2015 IEEE.
PY - 2016/3/21
Y1 - 2016/3/21
N2 - We have developed a cubic eggshell made of a cubic polycarbonate frame and 6 PDMS membranes. Development of embryo circulatory system was observed on the transparent side membrane. We hypothesized that blood vessels, which adhered on the side membrane for oxygen absorption, respond specifically to different oxygenated environment. To test this hypothesis, we designed patterned surfaces with selective oxygen permeation areas, and found that blood vessels formed selectively in oxygenated channels, which suggested a novel method for the control of blood vessel formation.
AB - We have developed a cubic eggshell made of a cubic polycarbonate frame and 6 PDMS membranes. Development of embryo circulatory system was observed on the transparent side membrane. We hypothesized that blood vessels, which adhered on the side membrane for oxygen absorption, respond specifically to different oxygenated environment. To test this hypothesis, we designed patterned surfaces with selective oxygen permeation areas, and found that blood vessels formed selectively in oxygenated channels, which suggested a novel method for the control of blood vessel formation.
UR - http://www.scopus.com/inward/record.url?scp=84966457651&partnerID=8YFLogxK
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U2 - 10.1109/MHS.2015.7438255
DO - 10.1109/MHS.2015.7438255
M3 - Conference contribution
AN - SCOPUS:84966457651
T3 - 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
BT - 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
Y2 - 23 November 2015 through 25 November 2015
ER -