Increased Frequency of HLA‐Cw3 and HLA‐Dw4 in Rheumatoid Arthritis

Andrew J. McMichael; Takehiko Sasazuki; Hugh O. McDevitt; Rose O. Payne

doi:10.1002/art.1780200501

Increased Frequency of HLA‐Cw3 and HLA‐Dw4 in Rheumatoid Arthritis

Andrew J. McMichael, Takehiko Sasazuki, Hugh O. McDevitt, Rose O. Payne

Research output: Contribution to journal › Article › peer-review

116 Citations (Scopus)

Abstract

Thirty‐nine patients with rheumatoid arthritis were HLA typed for the full range of A and B locus specificities and for Cw3 and Dw4. HLA‐Dw4 was significantly more frequent in patients (36%) than in controls (13%). The frequency of Cw3 was also increased, probably because this allele is in linkage disequilibrium with Dw4.

Original language	English
Pages (from-to)	1037-1042
Number of pages	6
Journal	Arthritis & Rheumatism
Volume	20
Issue number	5
DOIs	https://doi.org/10.1002/art.1780200501
Publication status	Published - Jun 1977
Externally published	Yes

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Rheumatology
Immunology
Pharmacology (medical)

Access to Document

10.1002/art.1780200501

Cite this

@article{93953618d6984e589b8114ae5e992fb1,

title = "Increased Frequency of HLA‐Cw3 and HLA‐Dw4 in Rheumatoid Arthritis",

abstract = "Thirty‐nine patients with rheumatoid arthritis were HLA typed for the full range of A and B locus specificities and for Cw3 and Dw4. HLA‐Dw4 was significantly more frequent in patients (36%) than in controls (13%). The frequency of Cw3 was also increased, probably because this allele is in linkage disequilibrium with Dw4.",

author = "McMichael, {Andrew J.} and Takehiko Sasazuki and McDevitt, {Hugh O.} and Payne, {Rose O.}",

year = "1977",

month = jun,

doi = "10.1002/art.1780200501",

language = "English",

volume = "20",

pages = "1037--1042",

journal = "Arthritis & Rheumatism",

issn = "0004-3591",

publisher = "John Wiley and Sons Ltd",

number = "5",

}

TY - JOUR

T1 - Increased Frequency of HLA‐Cw3 and HLA‐Dw4 in Rheumatoid Arthritis

AU - McMichael, Andrew J.

AU - Sasazuki, Takehiko

AU - McDevitt, Hugh O.

AU - Payne, Rose O.

PY - 1977/6

Y1 - 1977/6

N2 - Thirty‐nine patients with rheumatoid arthritis were HLA typed for the full range of A and B locus specificities and for Cw3 and Dw4. HLA‐Dw4 was significantly more frequent in patients (36%) than in controls (13%). The frequency of Cw3 was also increased, probably because this allele is in linkage disequilibrium with Dw4.

AB - Thirty‐nine patients with rheumatoid arthritis were HLA typed for the full range of A and B locus specificities and for Cw3 and Dw4. HLA‐Dw4 was significantly more frequent in patients (36%) than in controls (13%). The frequency of Cw3 was also increased, probably because this allele is in linkage disequilibrium with Dw4.

UR - http://www.scopus.com/inward/record.url?scp=0017506702&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017506702&partnerID=8YFLogxK

U2 - 10.1002/art.1780200501

DO - 10.1002/art.1780200501

M3 - Article

C2 - 869952

AN - SCOPUS:0017506702

SN - 0004-3591

VL - 20

SP - 1037

EP - 1042

JO - Arthritis & Rheumatism

JF - Arthritis & Rheumatism

IS - 5

ER -

Increased Frequency of HLA‐Cw3 and HLA‐Dw4 in Rheumatoid Arthritis

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this