TY - JOUR
T1 - Increased and more heterogeneous gadoxetic acid uptake of the liver parenchyma after hepatitis c virus eradication by direct antiviral agent
AU - Fujita, Nobuhiro
AU - Nishie, Akihiro
AU - Asayama, Yoshiki
AU - Ishigami, Kousei
AU - Nakayama, Tomohiro
AU - Ushijima, Yasuhiro
AU - Kakihara, Daisuke
AU - Takayama, Yukihisa
AU - Morita, Koichiro
AU - Ishimatsu, Keisuke
AU - Takao, Seiichiro
AU - Yoshizumi, Tomoharu
AU - Furusyo, Norihiro
AU - Honda, Hiroshi
N1 - Funding Information:
This work was supported by the Japan Society for the Pro-motion of Science (JSPS) KAKENHI (17K10407).
Funding Information:
This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (17K10407).
Publisher Copyright:
© 2020 Japanese Society for Magnetic Resonance in Medicine.
PY - 2020
Y1 - 2020
N2 - We evaluated the changes of gadoxetic acid uptake of the liver parenchyma after hepatitis C virus (HCV) eradication by direct-antiviral agent (DAA) therapy. The increase rate of the liver-to-muscle signal intensity ratio, the skewness and the kurtosis were calculated in the hepatobiliary phase. After sustained virological response, gadoxetic acid uptake of the liver parenchyma increased, but became heterogeneous. Our study proved that HCV eradication by DAA therapy could significantly affect gadoxetic acid uptake.
AB - We evaluated the changes of gadoxetic acid uptake of the liver parenchyma after hepatitis C virus (HCV) eradication by direct-antiviral agent (DAA) therapy. The increase rate of the liver-to-muscle signal intensity ratio, the skewness and the kurtosis were calculated in the hepatobiliary phase. After sustained virological response, gadoxetic acid uptake of the liver parenchyma increased, but became heterogeneous. Our study proved that HCV eradication by DAA therapy could significantly affect gadoxetic acid uptake.
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U2 - 10.2463/mrms.tn.2019-0183
DO - 10.2463/mrms.tn.2019-0183
M3 - Article
C2 - 32051362
AN - SCOPUS:85097132392
SN - 1347-3182
VL - 19
SP - 389
EP - 393
JO - Magnetic Resonance in Medical Sciences
JF - Magnetic Resonance in Medical Sciences
IS - 4
ER -
