TY - JOUR
T1 - Incidence, serum IgE and TARC/ccl17 levels in atopic dermatitis associated with other allergic diseases
T2 - An update from the Ishigaki cohort
AU - Takeuchi, Satosh
AU - Esaki, Hitokazu
AU - Furusyo, Norihiro
AU - Hayashida, Sayak
AU - Yamamura, Kazuhik
AU - Tsuji, Gak
AU - Takemura, Masak
AU - Hayashi, Jun
AU - Furue, Masutaka
N1 - Publisher Copyright:
© 2015 The Authors.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Population cohort studies are important for understanding the current status of the target disease and its relation to comorbidity, gender, age, or environmental factors. To better understand atopic dermatitis (AD) and its related diseases, we initiated in 2001 a population cohort study of nursery school children from Ishigaki Island, Okinawa, Japan. The cohort study comprised a dermatologist- based physical examination, questionnaire administration, and blood sample analysis. The mean prevalence of AD was 6.3%. Questionnaire-based bronchial asthma and egg allergy in the children and paternal and sibling AD were statistically significant risk factors for AD. Boys with AD had a high incidence of asthma that was coexistent with a high serum total immunoglobulin E level. Also a high incidence of egg allergy was associated with greater AD severity as assessed by TARC CCL17.
AB - Population cohort studies are important for understanding the current status of the target disease and its relation to comorbidity, gender, age, or environmental factors. To better understand atopic dermatitis (AD) and its related diseases, we initiated in 2001 a population cohort study of nursery school children from Ishigaki Island, Okinawa, Japan. The cohort study comprised a dermatologist- based physical examination, questionnaire administration, and blood sample analysis. The mean prevalence of AD was 6.3%. Questionnaire-based bronchial asthma and egg allergy in the children and paternal and sibling AD were statistically significant risk factors for AD. Boys with AD had a high incidence of asthma that was coexistent with a high serum total immunoglobulin E level. Also a high incidence of egg allergy was associated with greater AD severity as assessed by TARC CCL17.
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U2 - 10.2340/00015555-1989
DO - 10.2340/00015555-1989
M3 - Article
C2 - 25350554
AN - SCOPUS:84924953947
SN - 0001-5555
VL - 95
SP - 480
EP - 484
JO - Acta dermato-venereologica
JF - Acta dermato-venereologica
IS - 4
ER -