Incidence, diagnosis and treatment of popliteal artery entrapment syndrome in current vascular practice in Japan

Naoki Fujimura, Kyousuke Hosokawa, Hideaki Obara, Kimihiro Igari, Daijirou Akamatsu, Hidetoshi Matsumoto, Atsunori Asami, Shintaro Shibutani, Takurin Akiyoshi, Masao Nunokawa, Hirohisa Harada, Kyozo Inoue, Atsuhiro Koya, Tadashi Furuyama, Daisuke Sagara, Tsunehiro Shintani, Terutoshi Yamaoka, Yoshinobu Akiyama, Yoshinori Inoue, Katsuyuki Hoshina

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Few data regarding popliteal artery entrapment syndrome (PAES) is available in Japan. In this study, we investigated incidence, diagnosis and treatment of PAES in current vascular practice. A retrospective analysis of all patients with PAES visiting 31 participating institutes between 2003 and 2015 was conducted. Thirty-five limbs (28 patients) were identified during the 13-year study period, and the incidence of PAES was 0.12% of all peripheral artery disease cases revascularized. Mean age was 32.0 ± 16.9 years old, and 60 and more years old was 10.7%. Also, 92.9% were male and 39.3% were athletes. Most frequent initial symptoms were intermittent claudication in 23 limbs (65.7%); 4 limbs (11.4%) had chronic limb-threatening ischemia. CT scan was most frequently (94.3%) used for the diagnostic imaging followed by MRI (45.7%) and duplex ultrasound (45.7%). Stress test such as dorsal flexion during duplex ultrasound was used only in 28.6%. Thirty-two limbs (91.4%) received surgical treatment, including 23 arterial reconstructions (71.9%); there were no major perioperative complications. All patients achieved improvement of their symptoms, and the average ankle brachial index increased from 0.69 ± 0.22 to 1.00 ± 0.14 post-surgery. The average postoperative follow-up period was 26.0 months with only one reintervention during the follow-up. In conclusion, PAES was a rare condition and traditional surgical treatment was solid. However, given a broad spectrum of clinical feature of PAES and less usage of diagnostic duplex ultrasound with stress test, there might be a miss- or delayed diagnosis of PAES even in the current vascular practice.

Original languageEnglish
Pages (from-to)506-513
Number of pages8
JournalCardiovascular Intervention and Therapeutics
Issue number4
Publication statusPublished - Oct 2021

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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