Incidence and risk factors of postoperative delirium in cervical spine surgery

Takahiro Ushida, Takeshi Yokoyama, Yasuyo Kishida, Mika Hosokawa, Shinichirou Taniguchi, Shinsuke Inoue, Ryuichi Takemasa, Katsutoshi Suetomi, Young Chang P. Arai, Matthew McLaughlin, Toshikazu Tani

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)


Study Design. Retrospective clinical review and prospective report of postoperative delirium after cervical spine surgeries. Objective. To investigate factors contributing to the development of delirium after cervical surgery and see whether amended therapeutic protocols could improve or alter postoperative outcomes. Summary of Background Data. Important consequences of postoperative delirium for the orthopedic patients include impaired recovery and increased morbidity and mortality. Although its risk factors have been reported in orthopedic surgery, there are a very few reports regarding postoperative delirium in spine surgery. Methods. Eighty-one cervical myelopathy patients were retrospectively examined about the incidence of postoperative delirium and the risk factors. Similarly, 41 patients who received postoperative care under modified protocols were prospectively examined. Results. Postoperative delirium occurred more commonly in patients over 70 years and those with hearing impairment. Patients who received high-dose methylprednisolone (>1000 mg) demonstrated an increased incidence of postoperative delirium. Under modified protocol, we reduced the usage of methylprednisolone and encouraged free body movement with cervical orthosis immediately after surgery. The incidence of postoperative delirium was significantly lower under the modified protocol. Conclusion. Early commencement of mobilization after cervical spine surgery would be crucial to the prevention of postoperative delirium in the elderly.

Original languageEnglish
Pages (from-to)2500-2504
Number of pages5
Issue number23
Publication statusPublished - Nov 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Clinical Neurology


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