In vitro screening of angiotensin I-converting enzyme inhibitory activities in traditional plant medicines of Indonesia and Peru

Yuji Tsutsumi; Nozomi Fujii; Tomoaki Nishida; Ryo Soda; Ko Ichi Oshiman

In vitro screening of angiotensin I-converting enzyme inhibitory activities in traditional plant medicines of Indonesia and Peru

Yuji Tsutsumi, Nozomi Fujii, Tomoaki Nishida, Ryo Soda, Ko Ichi Oshiman

Research output: Contribution to journal › Article › peer-review

Abstract

A total of 110 extracts from 83 Indonesian traditional plant medicines and from 11 samples from Peru were subjected to the screening of angiotensin 1-converting enzyme (ACE) inhibitors by the in vitro ACE inhibitory assay at a fixed concentration, and the IC₅₀ values for the selected 17 extracts were determined. The 100% ethanol extract from Majakani (Quercus lusitanica) showed the highest inhibitory activity and its IC₅₀ was 5.7 μg/ml.

Original language	English
Pages (from-to)	7-13
Number of pages	7
Journal	Natural Medicines
Volume	54
Issue number	1
Publication status	Published - Feb 2000
Externally published	Yes

All Science Journal Classification (ASJC) codes

Drug Discovery
Complementary and alternative medicine
Pharmaceutical Science
Organic Chemistry

Cite this

@article{8c59eea7d566409486fc7cae97afa31c,

title = "In vitro screening of angiotensin I-converting enzyme inhibitory activities in traditional plant medicines of Indonesia and Peru",

abstract = "A total of 110 extracts from 83 Indonesian traditional plant medicines and from 11 samples from Peru were subjected to the screening of angiotensin 1-converting enzyme (ACE) inhibitors by the in vitro ACE inhibitory assay at a fixed concentration, and the IC50 values for the selected 17 extracts were determined. The 100% ethanol extract from Majakani (Quercus lusitanica) showed the highest inhibitory activity and its IC50 was 5.7 μg/ml.",

author = "Yuji Tsutsumi and Nozomi Fujii and Tomoaki Nishida and Ryo Soda and Oshiman, {Ko Ichi}",

year = "2000",

month = feb,

language = "English",

volume = "54",

pages = "7--13",

journal = "Natural Medicines",

issn = "1340-3443",

publisher = "Springer Japan",

number = "1",

}

TY - JOUR

T1 - In vitro screening of angiotensin I-converting enzyme inhibitory activities in traditional plant medicines of Indonesia and Peru

AU - Tsutsumi, Yuji

AU - Fujii, Nozomi

AU - Nishida, Tomoaki

AU - Soda, Ryo

AU - Oshiman, Ko Ichi

PY - 2000/2

Y1 - 2000/2

N2 - A total of 110 extracts from 83 Indonesian traditional plant medicines and from 11 samples from Peru were subjected to the screening of angiotensin 1-converting enzyme (ACE) inhibitors by the in vitro ACE inhibitory assay at a fixed concentration, and the IC50 values for the selected 17 extracts were determined. The 100% ethanol extract from Majakani (Quercus lusitanica) showed the highest inhibitory activity and its IC50 was 5.7 μg/ml.

AB - A total of 110 extracts from 83 Indonesian traditional plant medicines and from 11 samples from Peru were subjected to the screening of angiotensin 1-converting enzyme (ACE) inhibitors by the in vitro ACE inhibitory assay at a fixed concentration, and the IC50 values for the selected 17 extracts were determined. The 100% ethanol extract from Majakani (Quercus lusitanica) showed the highest inhibitory activity and its IC50 was 5.7 μg/ml.

UR - http://www.scopus.com/inward/record.url?scp=0034069263&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034069263&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0034069263

SN - 1340-3443

VL - 54

SP - 7

EP - 13

JO - Natural Medicines

JF - Natural Medicines

IS - 1

ER -

In vitro screening of angiotensin I-converting enzyme inhibitory activities in traditional plant medicines of Indonesia and Peru

Abstract

All Science Journal Classification (ASJC) codes

Other files and links

Fingerprint

Cite this