In vitro bioactive nano-crystalline TiO2 layers grown at glass-coating/titanium interface

Yongxing Liu, Kanji Tsuru, Satoshi Hayakawa, Akiyoshi Osaka

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


A new approach is presented to prepare a rutile layer on titanium substrates. According to this approach, pulverized glass, composed of 3CaO·4B2O3·3TiO2, is first developed on the substrate, heated up to 700 to 850°C, and then removed by soaking in hot water. During the heating process, rutile grew at the glass coating-substrate interface to form nano-sized crystallites. The rutile layer induced apatite formation within 3 d when soaked in simulated body fluid of the Kokubo recipe. Such in vitro bioactivity was attributed to many Ti-OH groups on the crystallite surface derived from hydrolysis of bonds at the crystallite-flux (matrix) interface like (rutile) -Ti-O-B or Ti-O-Ca-(the borate matrix).

Original languageEnglish
Pages (from-to)452-457
Number of pages6
JournalJournal of the Ceramic Society of Japan
Issue number1308
Publication statusPublished - Aug 2004
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • General Chemistry
  • Condensed Matter Physics
  • Materials Chemistry


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