In utero evaluation and the long-term prognosis of living infants with cystic hygroma

Yasuyuki Fujita, Shoji Satoh, Hideki Nakayama, Tomoaki Taguchi, Sachiyo Suita, Hitoo Nakano

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Objective: The aim is to evaluate the natural course and the long-term prognosis of cystic hygroma following live birth. Methods: Of 39 cases, 12 were excluded because of either artificial termination or intrauterine treatment. 27 cases were retrospectively classified into 2 groups based on the outcome, and the clinical profiles were compared. The long-term prognosis was analyzed for live births. Results: 5 (18.5%) and 22 (81.5%) cases resulted in live birth and fetal demise, respectively. Both the frequency of hydrops fetalis and the maximum size of the cyst were more significantly associated with a poor prognosis (p < 0.01). Of 5 live births, 3 cases with chromosomal or structural abnormalities were handicapped. Conclusions: Hydrops fetalis and cyst size are poor prognostic factors, and fetal chromosome and structural malformations should be taken into account when predicting the long-term prognosis. Copyright

Original languageEnglish
Pages (from-to)402-406
Number of pages5
JournalFetal Diagnosis and Therapy
Issue number6
Publication statusPublished - 2001

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Embryology
  • Radiology Nuclear Medicine and imaging
  • Obstetrics and Gynaecology


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