Improvement of measurement method for hydroxylated polychlorinated biphenyls (OH-PCBs) in blood samples using LC/MS/MS.

Kazuhiro Tobiishi; Shigeru Suzuki; Takashi Todaka; Hironori Hirakawa; Tsuguhide Hori; Jumboku Kajiwara; Teruaki Hirata; Takao Iida; Hiroshi Uchi; Masutaka Furue

Improvement of measurement method for hydroxylated polychlorinated biphenyls (OH-PCBs) in blood samples using LC/MS/MS.

Kazuhiro Tobiishi, Shigeru Suzuki, Takashi Todaka, Hironori Hirakawa, Tsuguhide Hori, Jumboku Kajiwara, Teruaki Hirata, Takao Iida, Hiroshi Uchi, Masutaka Furue

Surgery

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2 Citations (Scopus)

Abstract

Hydroxylated polychlorinated biphenyls (OH-PCBs) are well known as metabolites of PCBs in the human body. We improved a measurement method for OH-PCBs in blood samples using LC/MS/MS. A new 2 microm particle column was used, and the analytical conditions for the LC/MS/MS measurements were optimized. The improved method is more sensitive than the conventional method for 5g blood samples. And, this method is effective at determining the concentrations of OH-PCBs, PCBs and dioxins from the same sample without special treatment of the sample such as derivatization.

Original language	English
Pages (from-to)	128-135
Number of pages	8
Journal	Unknown Journal
Volume	104
Issue number	4
Publication status	Published - Apr 2013

All Science Journal Classification (ASJC) codes

Medicine(all)

Cite this

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title = "Improvement of measurement method for hydroxylated polychlorinated biphenyls (OH-PCBs) in blood samples using LC/MS/MS.",

abstract = "Hydroxylated polychlorinated biphenyls (OH-PCBs) are well known as metabolites of PCBs in the human body. We improved a measurement method for OH-PCBs in blood samples using LC/MS/MS. A new 2 microm particle column was used, and the analytical conditions for the LC/MS/MS measurements were optimized. The improved method is more sensitive than the conventional method for 5g blood samples. And, this method is effective at determining the concentrations of OH-PCBs, PCBs and dioxins from the same sample without special treatment of the sample such as derivatization.",

author = "Kazuhiro Tobiishi and Shigeru Suzuki and Takashi Todaka and Hironori Hirakawa and Tsuguhide Hori and Jumboku Kajiwara and Teruaki Hirata and Takao Iida and Hiroshi Uchi and Masutaka Furue",

year = "2013",

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T1 - Improvement of measurement method for hydroxylated polychlorinated biphenyls (OH-PCBs) in blood samples using LC/MS/MS.

AU - Tobiishi, Kazuhiro

AU - Suzuki, Shigeru

AU - Todaka, Takashi

AU - Hirakawa, Hironori

AU - Hori, Tsuguhide

AU - Kajiwara, Jumboku

AU - Hirata, Teruaki

AU - Iida, Takao

AU - Uchi, Hiroshi

AU - Furue, Masutaka

PY - 2013/4

Y1 - 2013/4

N2 - Hydroxylated polychlorinated biphenyls (OH-PCBs) are well known as metabolites of PCBs in the human body. We improved a measurement method for OH-PCBs in blood samples using LC/MS/MS. A new 2 microm particle column was used, and the analytical conditions for the LC/MS/MS measurements were optimized. The improved method is more sensitive than the conventional method for 5g blood samples. And, this method is effective at determining the concentrations of OH-PCBs, PCBs and dioxins from the same sample without special treatment of the sample such as derivatization.

AB - Hydroxylated polychlorinated biphenyls (OH-PCBs) are well known as metabolites of PCBs in the human body. We improved a measurement method for OH-PCBs in blood samples using LC/MS/MS. A new 2 microm particle column was used, and the analytical conditions for the LC/MS/MS measurements were optimized. The improved method is more sensitive than the conventional method for 5g blood samples. And, this method is effective at determining the concentrations of OH-PCBs, PCBs and dioxins from the same sample without special treatment of the sample such as derivatization.

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AN - SCOPUS:84886802306

SN - 1040-6182

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JF - Unknown Journal

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ER -

Improvement of measurement method for hydroxylated polychlorinated biphenyls (OH-PCBs) in blood samples using LC/MS/MS.

Abstract

All Science Journal Classification (ASJC) codes

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