Improvement of bioactivity of H2O2/TaCl5-treated titanium after subsequent heat treatments

Xiao Xiang Wang, Satoshi Hayakawa, Kanji Tsuru, Akiyoshi Osaka

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167 Citations (Scopus)


Commercially pure titanium was treated with a H2O2/3 mM TaCl5 solution at 80°C for various periods and a titania gel layer was formed on the surface. This gel remained amorphous when heating for 1 h below 200°C and transformed to anatase after heating between 300°and 600°C. The anatase titania gel layers were found to be bioactive as to deposit carbonate ion- incorporated apatite within 1 day of immersion in the Kokubo solution, whereas the amorphous layers did not deposit apatite within 7 days. The apatite particles were found to nucleate preferentially inside the cracks prevailing in the thicker gel layers of 1-h chemically treated specimens. After immersing for 2 days, the titanium specimens were almost completely covered by apatite. Elimination of peroxide radicals from the titania gel and formation of anatase upon subsequent heating are considered to be responsible for the enhanced ability of apatite deposition. (C) 2000 John Wiley and Sons, Inc.

Original languageEnglish
Pages (from-to)171-176
Number of pages6
JournalJournal of Biomedical Materials Research
Issue number1
Publication statusPublished - Aug 1 2000
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering


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