Improved visibility of colorectal flat tumors using image-enhanced endoscopy

Shiro Oka, Naoto Tamai, Hiroaki Ikematsu, Takuji Kawamura, Manabu Sawaya, Yoji Takeuchi, Toshio Uraoka, Tomohiko Moriyama, Hiroshi Kawano, Takahisa Matsuda

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Colonoscopy is considered the gold standard for detecting colorectal tumors; however, conventional colonoscopy can miss flat tumors. We aimed to determine whether visualization of colorectal flat lesions was improved by autofluorescence imaging and narrow-band imaging image analysis in conjunction with a new endoscopy system. Eight physicians compared autofluorescent, narrow-band, and chromoendoscopy images to 30 corresponding white-light images of flat tumors. Physicians rated tumor visibility from each image set as follows: +2 (improved), +1 (somewhat improved), 0 (equivalent to white light), -1 (somewhat decreased), and -2 (decreased). The eight scores for each image were totalled and evaluated. Interobserver agreement was also examined. Autofluorescent, narrow-band, and chromoendoscopy images showed improvements of 63.3% (19/30), 6.7% (2/30), and 73.3% (22/30), respectively, with no instances of decreased visibility. Autofluorescence scores were generally greater than narrow-band scores. Interobserver agreement was 0.65 for autofluorescence, 0.80 for narrow-band imaging, and 0.70 for chromoendoscopy. In conclusion, using a new endoscopy system in conjunction with autofluorescent imaging improved visibility of colorectal flat tumors, equivalent to the visibility achieved using chromoendoscopy.

Original languageEnglish
Pages (from-to)35-39
Number of pages5
JournalDigestive Endoscopy
Issue numberS1
Publication statusPublished - Apr 1 2015

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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