Impact of a 7.5-Fr Pancreatic Stent for Preventing Pancreatic Fistula after Pancreaticoduodenectomy

Tomohiro Iguchi, Takashi Motomura, Hideaki Uchiyama, Norifumi Iseda, Rintaro Yoshida, Hiroto Kayashima, Noboru Harada, Mizuki Ninomiya, Keishi Sugimachi, Takuya Honboh, Takashi Maeda, Noriaki Sadanaga, Hiroshi Matsuura

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Introduction: Pancreatic duct stents are widely used to reduce the incidence of postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD); however, small stents may cause adverse effects, such as occlusion. Recently, we have tried placing a 7.5-Fr pancreatic duct stent to achieve more effective exocrine output from the pancreas; however, the association between pancreatic duct stent size and POPF remains unknown. Methods: Sixty-five patients with soft pancreatic texture who underwent PD were retrospectively analyzed. After dividing the pancreas, a pancreatic duct stent (stent size 4.0 in 29 patients, 5.0 in 18, and 7.5 Fr in 18) was placed in the main pancreatic duct. Results: Twenty-five of 65 patients with soft pancreatic texture (38.5%) developed POPF. POPF became less frequent as the pancreatic duct stent size increased (p = 0.003). The factors associated with POPF development were a 7.5-Fr pancreatic duct stent (p = 0.005), 5.0-Fr pancreatic duct stent (p = 0.031), and male sex (p = 0.008). Pancreatic duct stent size and pancreatic duct diameter did not differ between the POPF and non-POPF groups. Discussion/Conclusions: In patients with a soft pancreas, the placement of a 7.5-Fr pancreatic duct stent may reduce the incidence of POPF.

Original languageEnglish
Pages (from-to)361-367
Number of pages7
JournalDigestive surgery
Issue number5
Publication statusPublished - Jan 1 2022

All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology


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