Image sensor with hybirid emission filter for in-vivo fluorescent imaging

In this paper, we report a method of fabricating an implantable image sensor equipped a bandpass hybrid filter for highly sensitive fluorescence observation. A hybrid filter that combines an interference filter and an absorption filter enables a high excitation light removal performance in an implantable image sensor that does not use a lens. In this study, a thin hybrid filter was successfully mounted on the image sensor using the transfer method by using a laser lift-off technique. The transferred filter has no crack. It was demonstrated that the prototype device exhibited high excitation light removal performance and was able to acquire a fluorescent image with high contrast.