Idiopathic mesenteric phlebosclerosis: Its clinico-phathological features and differential diagnosis

Takashi Yao, Minako Hirahashi

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1 Citation (Scopus)


Idiopathic mesenteric phlebosclerosis is a relatively rare disease, however, it has now been established as a single disease entity. Clinically it is characterized by the average age in the 6 th decade, a slightly higher prevalence in women, affecting only Asian patients (especially Japanese), and right-sided colon predominance. Calcification along the intestinal wall in plain abdominal X-ray images, and calcification along the mesenteric veins in CT scans are characteristic features. Histologically, perivascular collagen deposition, marked submucosal fibrosis and calcification in the veins are characteristic features, accompanied by minimal inflammation except for areas of erosion. Clinically, conservative management is common for asymptomatic patients and, surgical resection is generally accepted for the patients with stenosis, ulcers of the colon or other such symptoms. The cause of idiopathic mesenteric phlebosclerosis still remains unknown, however Chinese medicine, including some toxic agents, has been attracting attention as a factor in the development of idiopathic mesenteric phlebosclerosis. In the future, it is expected that preventive measure will be established by elucidating its cause.

Original languageEnglish
Pages (from-to)415-423
Number of pages9
Issue number3
Publication statusPublished - Mar 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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