Identification of the lantibiotic nisin q, a new natural nisin variant produced by lactococcus lactis 61-14 isolated from a river in japan

Takeshi Zendo; Masanori Fukao; Kyoko Ueda; Tomoko Higuchi; Jiro Nakayama; Kenji Sonomoto

doi:10.1271/bbb.67.1616

Identification of the lantibiotic nisin q, a new natural nisin variant produced by lactococcus lactis 61-14 isolated from a river in japan

Takeshi Zendo, Masanori Fukao, Kyoko Ueda, Tomoko Higuchi, Jiro Nakayama, Kenji Sonomoto

Systems Biology

Research output: Contribution to journal › Article › peer-review

123 Citations (Scopus)

Abstract

Lactococcus lactis 61-14 isolated from river water produced a bacteriocin active against a wide range of Gram-positive bacteria. N-terminal amino acid sequencing, mass spectral analysis of the purified bacteriocin, and genetic analysis using nisin-specific primers showed that the bacteriocin was a new natural nisin variant, termed nisin Q. Nisin Q and nisin A differ in four amino acids in the mature peptide and two in the leader sequence.

Original language	English
Pages (from-to)	1616-1619
Number of pages	4
Journal	Bioscience, Biotechnology and Biochemistry
Volume	67
Issue number	7
DOIs	https://doi.org/10.1271/bbb.67.1616
Publication status	Published - Jan 1 2003

All Science Journal Classification (ASJC) codes

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

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AU - Zendo, Takeshi

AU - Fukao, Masanori

AU - Ueda, Kyoko

AU - Higuchi, Tomoko

AU - Nakayama, Jiro

AU - Sonomoto, Kenji

PY - 2003/1/1

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Identification of the lantibiotic nisin q, a new natural nisin variant produced by lactococcus lactis 61-14 isolated from a river in japan

Abstract

All Science Journal Classification (ASJC) codes

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