Identification of domains participating in the substrate specificity and subcellular localization of the multidrug resistance proteins MRP1 and MRP2

Pharmacology, Toxicology and Pharmaceutical Science

• Multidrug Resistance Associated Protein 1 100%
• Multidrug Resistance-Associated Protein 2 90%
• Leukotriene C4 50%
• Etoposide 30%
• Protein 20%
• Glycine 20%
• Methotrexate 20%
• Anticarcinogen 20%
• Substrate Specificity 20%
• Chimeric Protein 20%
• P-Glycoprotein 20%
• Malignant Neoplasm 10%
• Drug Resistance 10%
• Peptidoleukotriene 10%

Biochemistry, Genetics and Molecular Biology

• Leukotriene C4 50%
• Protein 40%
• Subcellular Localization 40%
• Wild Type 20%
• Amino Acids 20%
• Enzyme Specificity 20%
• Multidrug Resistance 20%
• Fusion Protein 20%
• Methotrexate 20%
• Kinetics 10%
• N-Terminus 10%
• thought 10%
• C-Terminus 10%
• Membrane 10%
• Molecule 10%
• Drug Resistance 10%
• Membrane Vesicle 10%
• Immunofluorescence 10%
• Chimera 10%
• Organic Anion 10%