Hypertrophie cranial pachymeningitis due to aspergillus flavus

H. Murai, J. Kira, T. Kobayashi, I. Goto, H. Inoue, K. Hasuo

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58 Citations (Scopus)


A 59-year-old woman suffered from occipital headache and bilateral cranial nerve VII, VIII, IX, X, XI and right XII deficit after developing otitis media. Magnetic resonance imaging (MRI) showed a thickening of the dura mater which was enhanced by gadolinium-DTPA (Gd). Aspergillus flavus was identified from the culture of otorrhea. She was treated with miconazole, flucytosin and fluconazole, which resulted in an improvement of the clinical symptoms and a thinning of the Gd-enhanced lesions on MRI. This is the first case of hypertrophic cranial pachymeningitis caused by Asp. flavus infection.

Original languageEnglish
Pages (from-to)247-250
Number of pages4
JournalClinical Neurology and Neurosurgery
Issue number3
Publication statusPublished - Sept 1992

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology


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