TY - JOUR
T1 - Hydrosilanes are not always a reducing reagent
T2 - A ruthenium-catalyzed introduction of primary alkyl groups to electron-rich aromatic rings using esters as a source of the alkyl groups
AU - Nagashima, Hideo
AU - Kubo, Yuichi
AU - Kawamura, Mitsunobu
AU - Nishikata, Takashi
AU - Motoyama, Yukihiro
N1 - Funding Information:
This work was supported by Grant-in-Aid for Science Research on Priority Areas (No. 18064014 , Synergy of Elements) from Ministry of Education, Culture, Sports, Science, and Technology, Japan and Grant-in-Aid for Young Scientists (Start-up) ( 22850014 ).
PY - 2011/10/7
Y1 - 2011/10/7
N2 - A triruthenium cluster, (μ 3, η 2, η 3, η 5-acenaphthylene)Ru 3(CO) 7 effectively catalyzes primary-alkylation reaction of electron-rich aromatic rings using a combination of hydrosilane and ester as a source of the primary-alkyl group. The reaction involves electrophilic substitution of arenes by carbocationic species stabilized by a neighboring alkoxy or siloxy group generated during the reduction of esters giving alkylated arenes after reductive removal of the alkoxy or siloxy group at the benzylic position.
AB - A triruthenium cluster, (μ 3, η 2, η 3, η 5-acenaphthylene)Ru 3(CO) 7 effectively catalyzes primary-alkylation reaction of electron-rich aromatic rings using a combination of hydrosilane and ester as a source of the primary-alkyl group. The reaction involves electrophilic substitution of arenes by carbocationic species stabilized by a neighboring alkoxy or siloxy group generated during the reduction of esters giving alkylated arenes after reductive removal of the alkoxy or siloxy group at the benzylic position.
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U2 - 10.1016/j.tet.2011.08.033
DO - 10.1016/j.tet.2011.08.033
M3 - Article
AN - SCOPUS:84860389047
SN - 0040-4020
VL - 67
SP - 7667
EP - 7672
JO - Tetrahedron
JF - Tetrahedron
IS - 40
ER -