Human serum and particulate debris: Protein binding and macrophage activation

D. H. Sun; Y. Nakashima; W. J. Maloney; S. B. Goodman; D. J. Schurman; R. L. Smith

Human serum and particulate debris: Protein binding and macrophage activation

D. H. Sun, Y. Nakashima, W. J. Maloney, S. B. Goodman, D. J. Schurman, R. L. Smith

Research output: Contribution to conference › Paper › peer-review

Abstract

The mechanisms by which particulate debris stimulates periprosthetic bone resorption or osteolysis were studied by examining the extent of serum protein binding to TiAlV and polymethylmethacrylate (PMMA) particles obtained from soft tissue membranes which were harvested during revision surgery. Results show that both TiAlV and PMMA particles are effective in activating macrophages, thereby contributing to the loosening of prosthetics.

Original language	English
Pages	554
Number of pages	1
Publication status	Published - 1996
Externally published	Yes
Event	Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can Duration: May 29 1996 → Jun 2 1996

Other

Other	Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
City	Toronto, Can
Period	5/29/96 → 6/2/96

All Science Journal Classification (ASJC) codes

Materials Science(all)

Cite this

@conference{c4115ef34d8448df941e257986d46d94,

title = "Human serum and particulate debris: Protein binding and macrophage activation",

abstract = "The mechanisms by which particulate debris stimulates periprosthetic bone resorption or osteolysis were studied by examining the extent of serum protein binding to TiAlV and polymethylmethacrylate (PMMA) particles obtained from soft tissue membranes which were harvested during revision surgery. Results show that both TiAlV and PMMA particles are effective in activating macrophages, thereby contributing to the loosening of prosthetics.",

author = "Sun, {D. H.} and Y. Nakashima and Maloney, {W. J.} and Goodman, {S. B.} and Schurman, {D. J.} and Smith, {R. L.}",

year = "1996",

language = "English",

pages = "554",

note = "Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) ; Conference date: 29-05-1996 Through 02-06-1996",

}

TY - CONF

T1 - Human serum and particulate debris

T2 - Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)

AU - Sun, D. H.

AU - Nakashima, Y.

AU - Maloney, W. J.

AU - Goodman, S. B.

AU - Schurman, D. J.

AU - Smith, R. L.

PY - 1996

Y1 - 1996

N2 - The mechanisms by which particulate debris stimulates periprosthetic bone resorption or osteolysis were studied by examining the extent of serum protein binding to TiAlV and polymethylmethacrylate (PMMA) particles obtained from soft tissue membranes which were harvested during revision surgery. Results show that both TiAlV and PMMA particles are effective in activating macrophages, thereby contributing to the loosening of prosthetics.

AB - The mechanisms by which particulate debris stimulates periprosthetic bone resorption or osteolysis were studied by examining the extent of serum protein binding to TiAlV and polymethylmethacrylate (PMMA) particles obtained from soft tissue membranes which were harvested during revision surgery. Results show that both TiAlV and PMMA particles are effective in activating macrophages, thereby contributing to the loosening of prosthetics.

UR - http://www.scopus.com/inward/record.url?scp=0030388120&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030388120&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:0030388120

SP - 554

Y2 - 29 May 1996 through 2 June 1996

ER -

Human serum and particulate debris: Protein binding and macrophage activation

Abstract

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All Science Journal Classification (ASJC) codes

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