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Human obesity and point mutations of leptin and leptin receptor

Research output: Contribution to journalReview articlepeer-review

Abstract

Obesity-related genes were isolated and identified in these several years. Development of transgenic mice has clarified the molecular mechanisms of obesity. There have been reported point mutations of the genes correspond to leptin(ob-gene) and leptin receptor(db-gene). Thereby leptin is considered to be one of the most important regulators of energy metabolism also in human.

Original languageEnglish
Pages (from-to)571-577
Number of pages7
JournalNippon rinsho. Japanese journal of clinical medicine
Volume59
Issue number3
Publication statusPublished - Mar 2001
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • General Medicine

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