Human herpesvirus 6 encephalitis in a patient with adult T-cell leukemia/lymphoma

Kensaku Idutsu; Yasunobu Abe; Jun Otonari; Yoshimichi Tachikawa; Rie Ohtsuka; Ilseung Choi; Koichiro Muta; Ryoichi Takayanagi

Human herpesvirus 6 encephalitis in a patient with adult T-cell leukemia/lymphoma

Kensaku Idutsu
, Yasunobu Abe
, Jun Otonari
, Yoshimichi Tachikawa
, Rie Ohtsuka
, Ilseung Choi
, Koichiro Muta
, Ryoichi Takayanagi

Internal Medicine

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Human herpesvirus 6 (HHV-6) reactivates in immunocompromised patients, and HHV-6 encephalitis has often been reported as a complication of transplantation. We describe a 37-year-old woman with the acute type of adult T-cell leukemia/lymphoma who developed HHV-6 encephalitis before chemotherapy. The patient's main symptoms were disorientation and short-term memory loss. Magnetic resonance imaging of the brain showed a bilateral T2 prolongation within the temporal lobes, and HHV-6 DNA was detected in the cerebrospinal fluid (CSF). After treatment with ganciclovir, HHV-6 DNA disappeared from the CSF and the patient's symptoms gradually improved. HHV-6 encephalitis should be listed as a differential diagnosis of encephalopathy developing in immunocompromised patients.

Original language	English
Pages (from-to)	664-666
Number of pages	3
Journal	[Rinshō ketsueki] The Japanese journal of clinical hematology
Volume	48
Issue number	8
Publication status	Published - Aug 2007

All Science Journal Classification (ASJC) codes

General Medicine

Cite this

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title = "Human herpesvirus 6 encephalitis in a patient with adult T-cell leukemia/lymphoma",

abstract = "Human herpesvirus 6 (HHV-6) reactivates in immunocompromised patients, and HHV-6 encephalitis has often been reported as a complication of transplantation. We describe a 37-year-old woman with the acute type of adult T-cell leukemia/lymphoma who developed HHV-6 encephalitis before chemotherapy. The patient's main symptoms were disorientation and short-term memory loss. Magnetic resonance imaging of the brain showed a bilateral T2 prolongation within the temporal lobes, and HHV-6 DNA was detected in the cerebrospinal fluid (CSF). After treatment with ganciclovir, HHV-6 DNA disappeared from the CSF and the patient's symptoms gradually improved. HHV-6 encephalitis should be listed as a differential diagnosis of encephalopathy developing in immunocompromised patients.",

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T1 - Human herpesvirus 6 encephalitis in a patient with adult T-cell leukemia/lymphoma

AU - Idutsu, Kensaku

AU - Abe, Yasunobu

AU - Otonari, Jun

AU - Tachikawa, Yoshimichi

AU - Ohtsuka, Rie

AU - Choi, Ilseung

AU - Muta, Koichiro

AU - Takayanagi, Ryoichi

PY - 2007/8

Y1 - 2007/8

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AB - Human herpesvirus 6 (HHV-6) reactivates in immunocompromised patients, and HHV-6 encephalitis has often been reported as a complication of transplantation. We describe a 37-year-old woman with the acute type of adult T-cell leukemia/lymphoma who developed HHV-6 encephalitis before chemotherapy. The patient's main symptoms were disorientation and short-term memory loss. Magnetic resonance imaging of the brain showed a bilateral T2 prolongation within the temporal lobes, and HHV-6 DNA was detected in the cerebrospinal fluid (CSF). After treatment with ganciclovir, HHV-6 DNA disappeared from the CSF and the patient's symptoms gradually improved. HHV-6 encephalitis should be listed as a differential diagnosis of encephalopathy developing in immunocompromised patients.

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JF - [Rinshō ketsueki] The Japanese journal of clinical hematology

IS - 8

ER -

Human herpesvirus 6 encephalitis in a patient with adult T-cell leukemia/lymphoma

Abstract

All Science Journal Classification (ASJC) codes

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