Human beta defensin-3 engineered keratinocyte sheets constructed by a magnetic force-based tissue engineering technique

Akira Ito; Tetsuya Takahashi; Yoshinori Kawabe; Masamichi Kamihira

doi:10.1016/j.jbiosc.2009.04.004

Human beta defensin-3 engineered keratinocyte sheets constructed by a magnetic force-based tissue engineering technique

Akira Ito, Tetsuya Takahashi, Yoshinori Kawabe, Masamichi Kamihira

Molecular and Biochemical Systems Engineering

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

A multilayered keratinocyte sheet overexpressing human beta defensin-3 (HBD-3) gene was prepared by the magnetic force-based tissue engineering technique. The cell sheet demonstrated significant antimicrobial activity, indicating that the therapeutic introduction of HBD-3 gene into cell sheets may provide a new gene therapy strategy for infectious diseases.

Original language	English
Pages (from-to)	244-247
Number of pages	4
Journal	Journal of Bioscience and Bioengineering
Volume	108
Issue number	3
DOIs	https://doi.org/10.1016/j.jbiosc.2009.04.004
Publication status	Published - Sept 2009

All Science Journal Classification (ASJC) codes

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jbiosc.2009.04.004

Cite this

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title = "Human beta defensin-3 engineered keratinocyte sheets constructed by a magnetic force-based tissue engineering technique",

abstract = "A multilayered keratinocyte sheet overexpressing human beta defensin-3 (HBD-3) gene was prepared by the magnetic force-based tissue engineering technique. The cell sheet demonstrated significant antimicrobial activity, indicating that the therapeutic introduction of HBD-3 gene into cell sheets may provide a new gene therapy strategy for infectious diseases.",

author = "Akira Ito and Tetsuya Takahashi and Yoshinori Kawabe and Masamichi Kamihira",

note = "Funding Information: This work was supported in part by Grants-in-Aid for Scientific Research (nos. 19686049 and 20034043) from the ministry of Education, Sports, Science, and Technology, Japan.",

year = "2009",

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language = "English",

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AU - Ito, Akira

AU - Takahashi, Tetsuya

AU - Kawabe, Yoshinori

AU - Kamihira, Masamichi

N1 - Funding Information: This work was supported in part by Grants-in-Aid for Scientific Research (nos. 19686049 and 20034043) from the ministry of Education, Sports, Science, and Technology, Japan.

PY - 2009/9

Y1 - 2009/9

N2 - A multilayered keratinocyte sheet overexpressing human beta defensin-3 (HBD-3) gene was prepared by the magnetic force-based tissue engineering technique. The cell sheet demonstrated significant antimicrobial activity, indicating that the therapeutic introduction of HBD-3 gene into cell sheets may provide a new gene therapy strategy for infectious diseases.

AB - A multilayered keratinocyte sheet overexpressing human beta defensin-3 (HBD-3) gene was prepared by the magnetic force-based tissue engineering technique. The cell sheet demonstrated significant antimicrobial activity, indicating that the therapeutic introduction of HBD-3 gene into cell sheets may provide a new gene therapy strategy for infectious diseases.

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JF - Journal of Bioscience and Bioengineering

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ER -

Human beta defensin-3 engineered keratinocyte sheets constructed by a magnetic force-based tissue engineering technique

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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