Novel cage-type cyclophanes, which are constructed with two rigid macrocyclic skeletons, tetraaza[18.104.22.168]paracyclophanes, and four bridging segments composed of β-L-aspartyl-L-aspartyl residues and β-D-aspartyl-D-aspartyl residues individually, were prepared. Chiral host-guest interactions between the hosts and a hydrophobic guest, pamoic acid, were examined by circular dichroism spectroscopy in aqueous media.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry