Histological observation of eggs of the embryonic lethal mutation set in Bombyx mori

Yutaka Kawaguchi, Kazutaka Kawakami, Takahiro Kusakabe, Katsumi Koga

Research output: Contribution to journalArticlepeer-review


A mutation named Set, which has been characterized by abnormal larval traits, shows embryonic lethality as a pleiotropic effect. Light microscopic observations of the dying eggs without hatching of this mutation indicated that the epithelial cells of the midgut, especially the microvilli, were abnormal. Other tissues and organs of Set embryos were confirmed to develop fully, but massive yolk remained in the lumen of the midgut, indicating that yolk proteins were not utilized. We infer that the Set mutation brings about functional impairment of the midgut digestive/absorption system.

Original languageEnglish
Pages (from-to)101-106
Number of pages6
JournalJournal of Insect Biotechnology and Sericology
Issue number2
Publication statusPublished - Jun 2004

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • General Business,Management and Accounting
  • General Agricultural and Biological Sciences
  • Insect Science
  • Industrial and Manufacturing Engineering


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