Highly Enantioselective Cyclopropanation with Co(II)-Salen Complexes: Control of cis- and trans-Selectivity by Rational Ligand-Design

Tatsuo Niimi, Tatsuya Uchida, Ryo Irie, Tsutomu Katsuki

Research output: Contribution to journalArticlepeer-review

103 Citations (Scopus)

Abstract

Cyclopropanation of styrene derivatives with alkyl α-diazoacetate in the presence of the second-generation (salen)cobalt(II) complex 6 proceeded with excellent cis- and enantioselectivity. On the other hand, the cyclopropanation in the presence of complex 14 which was designed on the basis of the mechanism of asymmetric induction by complex 6 showed good trans- and excellent enantio-selectivity.

Original languageEnglish
Pages (from-to)79-88
Number of pages10
JournalAdvanced Synthesis and Catalysis
Volume343
Issue number1
DOIs
Publication statusPublished - Jan 2001

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

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