TY - JOUR
T1 - High concentrations of perfluorooctane sulfonate in mucus of tiger puffer fish Takifugu rubripes
T2 - a laboratory exposure study
AU - Honda, Masato
AU - Muta, Akemi
AU - Shimazaki, Akinari
AU - Akasaka, Taiki
AU - Yoshikuni, Michiyasu
AU - Shimasaki, Yohei
AU - Oshima, Yuji
N1 - Funding Information:
Funding information This study was partly supported by the Japan Society for the Promotion of Science Grant-in-Aid for Challenging Exploratory Research (KAKENHI) Grant Number 23651053.
Publisher Copyright:
© 2017, Springer-Verlag GmbH Germany.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Distribution of perfluorooctane sulfonate (PFOS) was investigated in tissues (plasma, blood clot, mucus, skin, liver, muscle, and gonad) of tiger puffer fish Takifugu rubripes. A single dose of PFOS was intraperitoneally injected at 0.1 mg/kg body weight with samples taken over a 14-day period. The highest concentration of PFOS was found in the plasma, 861 ng/mL at 14 days, followed by the mucus, liver, blood clot, gonads, muscles, and skin of fish. A gradual upward trend in PFOS concentration was observed in the mucus and liver whereas there was no change in the plasma, blood clot, gonad, muscle, and skin after the initial increase in PFOS concentrations following injection. No significant trend for estimated total PFOS content in whole body was observed during the experimental period. Relatively high concentrations of PFOS (690 ng/g ww after 14 days) were detected in body surface mucus that continuously oozes from the skin. These results may suggest that mucus is one of the elimination pathways of PFOS in tiger puffer fish.
AB - Distribution of perfluorooctane sulfonate (PFOS) was investigated in tissues (plasma, blood clot, mucus, skin, liver, muscle, and gonad) of tiger puffer fish Takifugu rubripes. A single dose of PFOS was intraperitoneally injected at 0.1 mg/kg body weight with samples taken over a 14-day period. The highest concentration of PFOS was found in the plasma, 861 ng/mL at 14 days, followed by the mucus, liver, blood clot, gonads, muscles, and skin of fish. A gradual upward trend in PFOS concentration was observed in the mucus and liver whereas there was no change in the plasma, blood clot, gonad, muscle, and skin after the initial increase in PFOS concentrations following injection. No significant trend for estimated total PFOS content in whole body was observed during the experimental period. Relatively high concentrations of PFOS (690 ng/g ww after 14 days) were detected in body surface mucus that continuously oozes from the skin. These results may suggest that mucus is one of the elimination pathways of PFOS in tiger puffer fish.
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U2 - 10.1007/s11356-017-0537-6
DO - 10.1007/s11356-017-0537-6
M3 - Article
C2 - 29098580
AN - SCOPUS:85032905807
SN - 0944-1344
VL - 25
SP - 1551
EP - 1558
JO - Environmental Science and Pollution Research
JF - Environmental Science and Pollution Research
IS - 2
ER -