Hepatocellular carcinoma with spontaneous regression: Report of the rare case

Yusuke Arakawa, Hiroki Mori, Toru Ikegami, Jun Hanaoka, Mami Kanamoto, Hirofumi Kanemura, Yuji Morine, Satoru Imura, Mitsuo Shimada

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


Spontaneous regression of a malignant tumor, including hepatocellular carcinoma, is extremely rare. A 78-year-old female with hepatitis B presented with a hepatocellular carcinoma, 3cm in size, in the lateral segment. During her work-up before surgery, over the period of a month, the tumor started to show spontaneous regression from the radiological and biochemical studies. A lateral segmentectomy of the liver was performed, and the pathologic study showed complete necrosis of the tumor with vigorous inflammatory cellular infiltration. The patient is now doing well without any evidence of recurrence. We herein report a case with hepatocellular carcinoma showing spontaneous regression, and review the associated literature.

Original languageEnglish
Pages (from-to)1770-1772
Number of pages3
Issue number86-87
Publication statusPublished - Sept 2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology


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