Growth of ring-shaped microtubule assemblies through stepwise active self-organisation

Daisuke Inoue, Arif Md Rashedul Kabir, Hiroyuki Mayama, Jian Ping Gong, Kazuki Sada, Akira Kakugo

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


The microtubule (MT)-kinesin system is a promising candidate for constructing artificial biomachines. The active self-organisation (AcSO) method has been developed to integrate MT filaments into highly organised assembled structures. The creation of ring-shaped MT assemblies is one of the outcomes of the organisation process and holds prospects for use in future nano-technological applications. However, making use of ring-shaped MT assemblies in practical applications requires further control of the size of these assemblies, which has not yet been addressed. In this work, we demonstrated AcSO of MTs in a stepwise manner inside an inert atmosphere. We show that in an inert atmosphere, AcSO could be performed several times (at least nine times), and as a result, this method successfully increased the thickness of ring-shaped MT assemblies.

Original languageEnglish
Pages (from-to)7061-7068
Number of pages8
JournalSoft Matter
Issue number29
Publication statusPublished - Aug 7 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • Condensed Matter Physics


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