Growth behavior of mesenchymal stem cell in 3D porous collagen scaffolds

Takaaki Arahira, Mitsugu Todo, Gouping Chen

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1 Citation (Scopus)


    In this study, porous structures of pure collagen and collagen/β-TCP composite material were developed as scaffolds for bone tissue engineering. Rat bone marrow mesenchymal stem cells (rMSC) were then cultured in the scaffolds with α-MEM based medium and a differentiation supplement. It was found that the compressive moduli of the scaffolds with rMSCs tended to increase with progress of proliferation and differentiation of the cells. Collagen/β-TCP composites were considered to be better scaffold material than pure collagen.

    Original languageEnglish
    Title of host publicationInterface Oral Health Science 2011
    PublisherSpringer Japan
    Number of pages3
    ISBN (Electronic)9784431540700
    ISBN (Print)9784431540694
    Publication statusPublished - Jan 1 2012

    All Science Journal Classification (ASJC) codes

    • General Dentistry


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