TY - JOUR
T1 - Gonadal and extragonadal functions of Ad4BP/SF-1
T2 - Developmental aspects
AU - Morohashi, Ken Ichirou
N1 - Funding Information:
The author thanks Mrs Hisae Tsuboi and Dr Ken Kawabe for the preparation of figures. This study was supported by a Grant-in-Aid for scientific research from the Ministry of Education, Science, Sports, and Culture of Japan, and grants from the Sumitomo Foundation, Suzuken Memorial Foundation, Uehara Memorial Foundation and Asahi Glass Foundation.
PY - 1999/7/1
Y1 - 1999/7/1
N2 - Gene disruption studies have clearly indicated that 4-binding protein/steroidogenic factor 1 (Ad4BP/SF-1), originally identified as a steroidogenic tissue-specific transcription factor, plays crucial roles in the process of non-steroidogenic as well as steroidogenic tissue differentiation. Although the precise mechanisms underlying differentiation of these tissues are still under investigation, spatial and temporal expression profiles of the gene encoding Ad4BP/SF-1 support its contribution to tissue development from the earliest stages of ontogeny.
AB - Gene disruption studies have clearly indicated that 4-binding protein/steroidogenic factor 1 (Ad4BP/SF-1), originally identified as a steroidogenic tissue-specific transcription factor, plays crucial roles in the process of non-steroidogenic as well as steroidogenic tissue differentiation. Although the precise mechanisms underlying differentiation of these tissues are still under investigation, spatial and temporal expression profiles of the gene encoding Ad4BP/SF-1 support its contribution to tissue development from the earliest stages of ontogeny.
UR - http://www.scopus.com/inward/record.url?scp=0033025545&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033025545&partnerID=8YFLogxK
U2 - 10.1016/S1043-2760(98)00142-8
DO - 10.1016/S1043-2760(98)00142-8
M3 - Review article
AN - SCOPUS:0033025545
SN - 1043-2760
VL - 10
SP - 169
EP - 173
JO - Trends in Endocrinology and Metabolism
JF - Trends in Endocrinology and Metabolism
IS - 5
ER -
