Glial Fibrillary Acidic Protein in Tuberous Sclerosis

Mizue Tobo, Yoshio Mitsuyama, Tsunehisa Kaku

Research output: Contribution to journalArticlepeer-review


Abstract: We examined two cases of tuberous sclerosis for the presence of glial fibrillary acidic protein (GFAP) using the immunoperoxidase technique. The majority of abnormal giant cells in the cerebral cortex showed no reaction to anti‐GFAP. Some abnormal cells in the cortical tuber and white matter showed a weak positive reaction. All of the subependymal tumor cells showed no GFAP in their cytoplasm. The abnormal giant cells in tuberous sclerosis,. morphologically similar to gemistocytic astrocyte, are not accompanied by antigenic properties of GFAP.

Original languageEnglish
Pages (from-to)95-100
Number of pages6
JournalPsychiatry and clinical neurosciences
Issue number1
Publication statusPublished - Mar 1983
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Neuroscience
  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health


Dive into the research topics of 'Glial Fibrillary Acidic Protein in Tuberous Sclerosis'. Together they form a unique fingerprint.

Cite this